Definition of complement
A nucleotide sequence in which each base is replaced by the complementary base of the given sequence: adenine (A) by thymine (T) or uracil (U), cytosine (C) by guanine (G), and vice versa.
Examples of complement in the following topics:
- In this concept, we will discuss the complement system.An array of approximately 20 types of soluble proteins, called a complement system, functions to destroy extracellular pathogens.
- Cells of the liver and macrophages synthesize complement proteins continuously.
- After the first few complement proteins bind, a cascade of sequential binding events follows in which the pathogen rapidly becomes coated in complement proteins.
- Complement proteins perform several functions.
- Certain complement proteins can combine to form attack complexes that open pores in microbial cell membranes.
- Around 20 soluble proteins comprise the complement system, which helps destroy extracellular microorganisms that have invaded the body.
- The genome of an organism consists of its entire complement of DNA, which encodes the genes that control the organism's characteristics.
- In another process, complement fixation, IgM and IgG in serum bind to antigens, providing docking sites onto which sequential complement proteins can bind.
- The combination of antibodies and complement enhances opsonization even further, promoting rapid clearing of pathogens.
- Each parent synthesizes gametes that contain only half of their chromosomal complement.
- Systemic lupus erythematosus may affect the heart, joints, lungs, skin, kidneys, central nervous system, or other tissues, causing tissue damage via antibody binding, complement recruitment, lysis, and inflammation .
- Unlike DNA replication, transcription results in an RNA complement that substitutes the RNA uracil (U) in all instances where the DNA thymine (T) would have occurred.
- These probes will seek their complement among the base pairs of an individual’s genome.
- The antigen-antibody complex stimulates the complement system described previously, destroying the cell bearing the antigen.
- Similarly, all cells contain the same full complement of DNA, but each type of cell only “reads” the portions of DNA that are relevant to its own functioning.