mononuclear phagocyte system(noun)
Definition of mononuclear phagocyte system
he mononuclear phagocyte system (MPS) is a part of the immune system that consists of the phagocytic cells located in reticular connective tissue. The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen. The Kupffer cells of the liver and tissue histiocytes are also part of the MPS.
Examples of mononuclear phagocyte system in the following topics:
- The spleen plays important roles in regards to red blood cells (also referred to as erythrocytes) and the immune system.
- As a part of the mononuclear phagocyte system, it metabolizes hemoglobin removed from senescent erythrocytes.
- It is one of the centers of activity of the mononuclear phagocyte system and can be considered analogous to a large lymph node, as its absence leads to a predisposition toward certain infections.
- The spleen is part of the lymphatic system.
- As a major lymphoid organ and a central player in the mononuclear phagocyte system, the spleen retains the ability to produce lymphocytes and, as such, remains a hematopoietic organ.
- The spleen, similar to a large lymph node, acts primarily as a blood filter in the mononuclear phagocyte system of the immune system.