Adrenaline (epinephrine) reacts with both α and βadrenoreceptors, causing vasoconstriction and vasodilation, respectively.
The result is that high levels of circulating epinephrine cause vasoconstriction.
Common (or still unspecified) effects include: vasoconstriction of cardiac arteries (coronary artery), vasoconstriction of veins, and decreased motility of smooth muscle in the gastrointestinal tract. α1-adrenergic receptors are members of the G protein-coupled receptor superfamily.
It causes vasoconstriction in many blood vessels, including those of the skin, gastrointestinal system, kidney (renal artery) and brain.