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Lactogenesis, or the process of changes to the mammary glands to begin producing milk, begins during the late stages of pregnancy. The delivery of the placenta, and the resulting dramatic reduction in progesterone, estrogen, and HPL levels, stimulates milk production.
Colostrum is the first milk a breastfed baby receives. It contains higher amounts of white blood cells and antibodies than mature milk, and is especially high in immunoglobulin A, which coats the lining of the baby's immature intestines, helping to prevent pathogens from invading the baby's system.
(1) The secretion of milk from the mammary gland of a female mammal. (2) The process of providing the milk to the young; breastfeeding. (3) The period of time that a mother lactates to feed her young; lactation period.
A form of milk produced by the mammary glands in late pregnancy and the few days after giving birth. Human and bovine colostrum is thick and yellowish. In humans, it has high concentrations of nutrients and antibodies, but it is small in quantity.
Lactation describes the secretion of milk from the mammary glands and the period of time that a mother lactates to feed her young. The process occurs in all female mammals, although it predates mammals. In humans the process of feeding milk is called breastfeeding or nursing.
In most species milk comes out of the mother's nipples ; however, the platypus (a non-placental mammal) releases milk through ducts in its abdomen. In only one species of mammal, the Dayak fruit bat, is milk production a normal male function. In some other mammals, the male may produce milk as the result of a hormone imbalance. This phenomenon may also be observed in newborn infants as well (for instance witch's milk). Galactopoiesis is the maintenance of milk production. This stage requires prolactin (PRL) and oxytocin.
The chief function of lactation is to provide nutrition and immune protection to the young after birth. In almost all mammals, lactation induces a period of infertility, which serves to provide the optimal birth spacing for survival of the offspring.
By the fifth or sixth month of pregnancy, the breasts are ready to produce milk. During the latter part of pregnancy, the woman's breasts enter into the Lactogenesis I stage. This is when the breasts make colostrum (see below), a thick, sometimes yellowish fluid. At this stage, high levels of progesterone inhibit most milk production. It is not a medical concern if a pregnant woman leaks any colostrum before her baby's birth, nor is it an indication of future milk production.
At birth, prolactin levels remain high, while the delivery of the placenta results in a sudden drop in progesterone, estrogen, and HPL levels. This abrupt withdrawal of progesterone in the presence of high prolactin levels stimulates the copious milk production of Lactogenesis II. When the breast is stimulated, prolactin levels in the blood rise, peak in about 45 minutes, and return to the pre-breastfeeding state about three hours later. The release of prolactin triggers the cells in the alveoli to make milk.
Colostrum is the first milk a breastfed baby receives. It contains higher amounts of white blood cells and antibodies than mature milk, and is especially high in immunoglobulin A (IgA), which coats the lining of the baby's immature intestines, and helps to prevent pathogens from invading the baby's system. Secretory IgA also helps prevent food allergies. Over the first two weeks after the birth, colostrum production slowly gives way to mature breast milk.
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