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Tubular reabsorption is the process by which solutes and water are removed from the tubular fluid and transported into the blood.
Describe the process of tubular reabsorption in kidney physiology
Proper function of the kidney requires that it receives and adequately filters blood.
Reabsorption is a two-step process beginning with the active or passive extraction of substances from the tubule fluid into the renal interstitium, and then the transport of these substances from the interstitium into the bloodstream.
These processes are mainly driven by active transport.
Proper function of the kidney requires that it receives and adequately filters blood. This is performed at a microscopic level by many hundreds of thousands of filtration units called renal corpuscles, each of which is composed of a glomerulus and a Bowman's capsule. A universally accepted way to assess efficient renal function is to estimate the rate of filtration, called the glomerular filtration rate (GFR).
Tubular reabsorption is the process by which solutes and water are removed from the tubular fluid and transported into the blood. It is called reabsorption (not absorption) because these substances have already been absorbed previously, usually in the intestines.
Reabsorption is a two-step process beginning with the active or passive extraction of substances from the tubular fluid into the renal interstitium (the connective tissue that surrounds the nephrons); then these substances are transported from the interstitium into the bloodstream. These transport processes are driven by Starling forces, diffusion, and active transport.
Diagram showing the basic physiologic mechanisms of the kidney and the three steps involved in urine formation.
This reabsorption process allows water (H2O) to pass from the glomerular filtrate back into the circulatory system. Glucose and various amino acids are also reabsorbed into the circulatory system. Glomerular filtrate is then separated into two forms: reabsorbed filtrate and non-reabsorbed filtrate. The non-reabsorbed filtrate is then known as tubular fluid as it passes through the collecting duct to be processed into urine.
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active transport of water, passive transport of glucose into peritubular capillary network, an estimate of glomerular filtration rate indicating passage of tubular fluid to circulatory system, continuous passage of tubular fluid into peritubular capillary network and back again, and active and passive transport of substances (e.g. glucose) and water from tubular fluid to the blood